Sequential testing install#

Alpha and/or beta spent at each stage is reported. Corresponding P-Value boundaries are given for each boundary statistic. Futility boundaries can be binding or non-binding. Boundaries can be computed based on popular alpha- and beta-spending functions (O’Brien-Fleming Analog, Pocock Analog, Hwang-Shih-DeCani Gamma family, linear) or custom spending functions, or boundaries may be input directly, if desired. The spacing of the stages can be equal or custom specified. For one- and two-sided tests, efficacy and/or futility boundaries can be generated. Superiority by a Margin Tests for One Poisson Rate (Simulation)Įach of these procedures can be used to determine power, sample size and/or boundaries for the corresponding group-sequential test.Non-Inferiority Tests for One Poisson Rate (Simulation).Tests for One Poisson Rate (Simulation).Superiority by a Margin Tests for Two Poisson Rates (Simulation).Non-Inferiority Tests for Two Poisson Rates (Simulation).Tests for Two Poisson Rates (Simulation).Superiority by a Margin Tests for One Hazard Rate (Simulation).Non-Inferiority Tests for One Hazard Rate (Simulation).Superiority by a Margin Tests for Two Hazard Rates (Simulation).Non-Inferiority Tests for Two Hazard Rates (Simulation).Tests for Two Hazard Rates (Simulation).Logrank Tests of Two Survival Curves assuming Proportional Hazards.Logrank Tests of Two Survival Curves assuming Exponential Survival.Superiority by a Margin Tests for Two Proportions using Odds Ratios (Simulation).Superiority by a Margin Tests for Two Proportions using Ratios (Simulation).Superiority by a Margin Tests for Two Proportions using Differences (Simulation).Superiority by a Margin Tests for Two Proportions (Simulation).Non-Inferiority Tests for Two Proportions using Odds Ratios (Simulation).Non-Inferiority Tests for Two Proportions using Ratios (Simulation).Non-Inferiority Tests for Two Proportions using Differences (Simulation).Non-Inferiority Tests for Two Proportions (Simulation).Tests for Two Proportions using Odds Ratios (Simulation).Tests for Two Proportions using Ratios (Simulation).Tests for Two Proportions using Differences (Simulation).Tests for Two Proportions – Unequal n’s.Superiority by a Margin T-Tests for Two Means (Simulation).Non-Inferiority T-Tests for Two Means (Simulation).

Superiority by a Margin Tests for Two Means with Known Variances (Simulation).Non-Inferiority Tests for Two Means with Known Variances (Simulation).Non-Inferiority Tests for Two Means – Mann-Whitney Test.Tests for Two Means (Simulation) General Assumptions – Mann-Whitney Test.Tests for Two Means (Simulation) General Assumptions.Tests for Two Means (Simulation) Assuming Normality.Tests for Two Means with Known Variances (Simulation).Tests for One Mean with Known Variance (Simulation).The various group-sequential sample size calculation procedures in PASS allow you to study the power and sample size for an expanding list of scenarios: For more details about group-sequential analysis and sample size re-estimation in NCSS, you can click here.

Sequential testing install#

For more details about group-sequential tests in PASS, we recommend you download and install the free trial of the software. The group-sequential tools in PASS are easy-to-use and validated for accuracy. Sample Size for Group-Sequential Tests in PASS PASS includes procedures for power analysis and sample size calculations for many different one-sample and two-sample group-sequential cases.